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Significant interaction between the groups and occasion of assessment occurred.

Significant reductions in the total scores on Beck Depression Inventory (BDI) and Hamilton Rating Scale for Depression (HRSD) occurred on successive occasions in all three groups. They were assessed at recruitment and weekly thereafter for four weeks. This study compared the relative antidepressant efficacy of SKY in melancholia with two of the current standard treatments, electroconvulsive therapy (ECT) and imipramine (IMN).Ĭonsenting, untreated melancholic depressives (n=45) were hospitalized and randomized equally into three treatment groups. The antidepressant efficacy of SKY was demonstrated in dysthymia in a prospective, open clinical trial. Sudarshan Kriya Yoga (SKY) is a procedure that involves essentially rhythmic hyperventilation at different rates of breathing.